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cogenomic Testing

Pharmacogenomic (PGx) testing combines the knowledge of how drugs work (pharmacology) with the science of the human genome (genomics). It assesses the impact of genetic factors on an individual’s response to drugs. A participant’s complete drug regimen is reviewed, including their drug-gene and multi-drug interactions and phenoconversions. Interventions may include monitoring or changing medications and altering dosages.

DNA strands.

PGx in practice

When evaluating patient responses to medication therapy, providers may wonder:

  • Why does this drug work for one patient but not another?
  • Why does this patient need much more (or much less) than the standard dose of the drug for it to be effective?
  • Why does this patient have side effects, while others do not, even though the drug and dose are similar?

Pharmacogenomic testing, also called drug-gene testing, can help answer these questions and guide more precise, individualized prescribing. Using these results, a clinical pharmacist from CareVention HealthCareTM (CVHC) provides a personalized consultation for prescribers—and provide years of benefits.

“It’s a different way to practice. It’s reinventing the way you think about prescribing.”

–PACE medical director

Pharmacogenomic testing explained

Watch this webinar on the benefits of precision pharmacogenomic-guided pharmacotherapy for Programs of All-Inclusive Care for the Elderly (PACE) participants was presented by Calvin H. Knowlton, Chairman and CEO of Tabula Rasa HealthCare (TRHC); Orsula V. Knowlton, President and Chief Marketing/New Business Development Officer of TRHC; and Ankur Patel, Chief Medical Officer of TRHC.

The basics

Robert Alesiani, PharmD, BCGP, Chief Pharmacotherapy Officer, Tabula Rasa HealthCare, presents the benefits of testing participants and the process of PGx testing.

The value and ROI

George W. Brett, MD, Senior Vice President of Consulting and Chief Medical Officer, Capstone Risk AdjustmentTM, and former PACE Medical Director, describes the results when his program implemented a PGx testing program.

Or explore this study on the return on investment (ROI) associated with PGx testing for clinical pharmacies.


The results

Discover how two programs utilized PGx testing for improved outcomes:

PACE case: Individualizing medication recommendations using pharmacogenomic test results

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TRU PACE: Innovative pharmacy solutions for a PACE start-up

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